Ketanserin tartrate ( R41468 tartrate )

产品货号. M16108 CAS No. 83846-83-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Ketanserin tartrate
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

A high-affinity, non-selective antagonist of 5-HT2 receptor with Ki of 2-3 nM for 5-HT2A and 28 nM for 5-HT2C.
产品描述

A high-affinity, non-selective antagonist of 5-HT2 receptor with Ki of 2-3 nM for 5-HT2A and 28 nM for 5-HT2C; also has a high affinity antagonist for the H1 receptor (Ki= 2 nM) and α1-adrenergic receptor (Ki=40 nM); an antihypertensive agent.Hypertension Approved
同义词

R41468 tartrate
通路

Endocrinology/Hormones
靶点

5-HT Receptor
受体

5-HT Receptor
研究领域

Cardiovascular Disease
适应症

Hypertension

CAS Number

83846-83-7
分子量

545.51
分子式

C26H28FN3O9
纯度

>98% (HPLC)
溶解度

H2O: 30 mg/mL (Need ultrasonic and warming)
SMILES

O=C(N1CCN2CCC(C(C3=CC=C(F)C=C3)=O)CC2)NC4=C(C=CC=C4)C1=O.O[C@H]([C@H](C(O)=O)O)C(O)=O
化学全称

2,4(1H,3H)-Quinazolinedione, 3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-, (2R,3R)-2,3-dihydroxybutanedioate (1:1)

1. Creed-Carson M, et al. Behav Brain Res. 2011 Jun 1;219(2):273-9.
2. Catafau AM, et al. J Cereb Blood Flow Metab. 2010 May;30(5):985-93.

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